Wednesday, September 27, 2006

I KNEW IT !!!!!!!!!!!!!!!!!!!!!!

...been saying it for years. Finally, it's in print. Believe me now? HA!

Too much testosterone kills brain cells

POSTED: 3:23 p.m. EDT, September 27, 2006
WASHINGTON (Reuters) -- Too much testosterone can kill brain cells, researchers say, in a finding that may help explain why steroid abuse can cause behavior changes such as aggressiveness and suicidal tendencies.

Tests on brain cells in lab dishes showed that while a little of the male hormone is good, too much of it causes cells to self-destruct in a process similar to that seen in brain illnesses such as Alzheimer's.

"Too little testosterone is bad, too much is bad but the right amount is perfect," said Barbara Ehrlich of Yale University in Connecticut, who led the study.

Testosterone is key to the development, differentiation and growth of cells and is produced by both men and women, although men produce about 20 times more of the hormone.

It can also be abused, and recent scandals have involved athletes who use the hormone, or steroids that turn into testosterone in the body, for an unfair advantage.

"Other people have shown that high levels of steroid can cause behavioral changes," Ehrlich said in a telephone interview.

"We can show that when you have high levels of steroids, you have high testosterone and that can destroy the nerve cells. We know that when you lose brain cells you lose function."

Ehrlich's team tried the same thing with the "female" hormone estrogen, just to be fair.

"We were surprised, but it actually looks like estrogen is neuroprotective. If anything, there is less cell death in the presence of estrogen," she said.

Writing in the Journal of Biological Chemistry, Ehrlich and colleagues said their findings meant people should think twice about supplementing with testosterone, even if it does build muscle mass and aid recovery after exercise.

"These effects of testosterone on neurons will have long-term effects on brain function," they wrote.

"Next time a muscle-bound guy in a sports car cuts you off on the highway, don't get mad -- just take a deep breath and realize that it might not be his fault," Ehrlich said in a statement.

The cells die via a process called apoptosis, also known as cell suicide or programmed cell death.

"Apoptosis is an important thing for the brain -- the brain needs to weed out some of the cells. But when it happens too frequently, you lose too many cells and causes problems."

A similar process is seen in Alzheimer's disease, the most common cause of dementia in the United States, affecting an estimated 4.5 million Americans, and Huntington's disease, another fatal brain illness.

"Our results suggest that the responses to elevated testosterone can be compared with these pathophysiological conditions," the researchers wrote.

Monday, September 11, 2006

Sept 11, 2001

We still see the world from this window. This view, on this day, has shaped our world and our personal perspectives. It was the lack of reaction to this event by those in the group I belonged, that changed my life irrevocably. Those who died on Sept 11, 2001 did not die in vain. It took every single one of those lives to make us realize that we were asleep and had to wake up. Apathy demands a sacrifice. Greater apathy demands greater sacrifice. Those people did not die in vain...unless we choose to continue our apathy and demand more lives in payment.

Thursday, September 07, 2006

It FITS!!!

JJ's Sweater
Patton's Classic Merino Wool, size 6 Addi Turbo
Elizabeth Zimmerman's EP Sweater formula
Cable stitch patterns chosen from Barbara Walker's Collections
Model is JJ but he asked that I not include his head :)

Sunday, September 03, 2006

Hey CHRISTINE!!!!...

It's DONE!
It's JJ's Aran sweater of course. It's taking a bath just now but I couldnt' wait to announce it's finished. As soon as it's blocked and dry I'll take a pic of the boy in it.

and a little gratuitous cute.
These are FA kits from CCR's Missy, a Chestnut FA doe. She's a real sweetheart and so are the babies. They are all 6 weeks old. The Orange is a doe and there is a black doe that's not pictured, the rest are bucks. I 'may' choose to keep the Orange, I'm not sure yet, but the rest will be for sale. These are NOT pure pedigreed and may (small chance) carry the Satin gene so they are sold as woolers. They can be shown, but not granded. Email me if you have interest.